Registered Nurse (RN) Endocrine Licensure Exam

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Prepare for the RN Endocrine Licensure Exam with our comprehensive quiz. Test your knowledge with multiple-choice questions and get explanations for each answer. Ace your exam!

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Which of the following statements is true regarding the action of Propylthiouracil (PTU)?

It stabilizes thyroid hormone levels immediately.
It must be taken with a full glass of juice.
It is safe for use during the second trimester of pregnancy.
It inhibits the synthesis of thyroid hormones in the thyroid gland.

The correct answer is: It inhibits the synthesis of thyroid hormones in the thyroid gland.

The statement regarding Propylthiouracil (PTU) that indicates it inhibits the synthesis of thyroid hormones in the thyroid gland is accurate because PTU functions by blocking the enzyme thyroid peroxidase, which plays a crucial role in the iodination of tyrosine residues in the synthesis of thyroxine (T4) and triiodothyronine (T3). This inhibition effectively reduces the production of these hormones, helping to manage conditions like hyperthyroidism by decreasing hormone levels in the bloodstream. The action of PTU is especially important in clinical settings where rapid control of thyroid hormone levels is required, but its effects may take several weeks to be fully realized. Understanding the mechanism of action helps in recognizing how this medication fits into treatment plans for thyroid disorders.