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Hypoglycemia is a well-known side effect of sulfonylureas, which are oral medications used to manage blood glucose levels in individuals with type 2 diabetes. These drugs work by stimulating the pancreas to release more insulin, thereby lowering blood glucose levels. However, this mechanism can sometimes lead to an excessive reduction in blood sugar, resulting in hypoglycemia.

Patients taking sulfonylureas must be aware of the signs and symptoms of hypoglycemia, which can include sweating, dizziness, confusion, and weakness, among others. Management typically includes monitoring blood glucose levels regularly and knowing how to treat low blood sugar episodes promptly.

In contrast, weight loss is typically associated with medications like GLP-1 receptor agonists rather than sulfonylureas, which may sometimes lead to weight gain. Increased thirst is more commonly linked to poorly controlled diabetes and hyperglycemia rather than to the use of sulfonylureas. Similarly, vision changes are not a direct side effect of sulfonylureas; they could be indicative of uncontrolled blood sugar levels or other diabetic complications.